This course provides a new basis forthe design of integrated chemical processes. The ability to predict, at the outset, achievable design targets that have a sound scientific basis is fundamental to the approach. These targets relate to energy, capital and raw materials, costs and flexibility. Topics will include review of basic thermodynamic concepts, capital/energy trade-off, process integration multiple utilities, process/utility interface, reactors and separators in the context of overallprocess power optimization, design for flexibility, total sites layout, batch processes and process plant retrofit.